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Over the last few decades, technology has existed to evaluate the cytotoxic effects of single-agent and combination chemotherapy on cancer cell lines derived from an individual patient's tumor specimens. However, investigators and clinicians have been frustrated as the fruit of this technologya reliable and reproducible assay to help them treat their patients with the agent or agents most likely to benefit themhas yet to be proven.
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A very simple study appeared in the August edition of the American Journal of Obstetrics and Gynecology. It dealt with the ability of clinicians to precisely determine the position of the fetal head in the maternal pelvis during the second stage of labor.
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Although safer than traditional colonoscopy, virtual colonoscopys lower sensitivity and efficacy coupled with the increased cost would rule against recommending this procedure at the current time.
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In a prospective, multicenter study, Cristofanilli and colleagues tested 177 patients with clinically detectable metastatic breast cancer for levels of circulating tumor cells both before and after the initiation of various forms of therapy. The response to therapy was followed using standard clinical detection, but blood samples were also collected to determine the burden of tumor cells in the circulation.
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Erythromycin and the Risk of Sudden Death; Vaccine Shortage Putting Americans At Risk; FDA Actions.
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The present study involves yet another analysis of the Nurses Health Study, which began in 1976 when 121,700 female registered nurses 30-55 years of age returned a questionnaire about their medical history and health-related behaviors.
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The latest news from the womens health initiative (WHI) includes 3 noteworthy reports: the news release announcing the cancellation of the estrogen-only arm of the clinical trial,1 a comparison of the participants in the 2 clinical trial arms(estrogen-progestin and estrogen-only),2 and the updated, adjudicated lorectal cancer results from the estrogen-progestin arm.3
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his retrospective review summarizes the clinical outcome and safety among 141 patients who were treated with boric acid and flucytosine for culture-proven Candida glabrata. These data were collected at both Wayne State University School of Medicine and Ben Gurion University.
