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Smith and colleagues performed a case-control study of venous thrombosis and hormone users in postmenopausal women registered in a large health maintenance organization (the Group Health Cooperative) in the state of Washington.
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Two premenopausal patients with resis tant endometriosis were successfully treated with a combination of the aromatase inhibitor anastrozole, Prometrium, calcitrol, and rofecoxib. Both patients had been diagnosed with endometriosis via laparoscopy, and had undergone GnRH suppression.
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Nearly 70% of patients achieving a CR after primary therapy eventually recurred. Most recurrences occurred more than 6 months from completion of primary chemotherapy, and the use of second line agents at the time of recurrence was effective.
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Results from the estrogen-progestin arm of the Womens Health Initiative confirm (after central adjudication of the diagnoses) an increase in venous thrombosis associated with a standard dose of postmenopausal hormone therapy.
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The present study involves yet another analysis of the Nurses Health Study, which began in 1976 when 121,700 female registered nurses 30-55 years of age returned a questionnaire about their medical history and health-related behaviors.
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Erythromycin and the Risk of Sudden Death; Vaccine Shortage Putting Americans At Risk; FDA Actions.
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In a prospective, multicenter study, Cristofanilli and colleagues tested 177 patients with clinically detectable metastatic breast cancer for levels of circulating tumor cells both before and after the initiation of various forms of therapy. The response to therapy was followed using standard clinical detection, but blood samples were also collected to determine the burden of tumor cells in the circulation.
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Although safer than traditional colonoscopy, virtual colonoscopys lower sensitivity and efficacy coupled with the increased cost would rule against recommending this procedure at the current time.