OB/GYN Clinical Alert
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Vaginal Misoprostol vs. Prostaglandin E2 Pessary for Induction of Labor at Term
In this randomized, noninferiority, clinical trial of pregnant women who underwent induction of labor with misoprostol compared to dinoprostone, the rate of vaginal delivery within 24 hours was higher in the misoprostol group. Maternal satisfaction, assessed by a visual analog scale, also was higher. Although the noninferiority of dinoprostone to misoprostol could not be demonstrated, the clinical risk-to-benefit ratio justifies the use of both drugs.
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Highlights from the CDC’s Updated 2021 Sexually Transmitted Infections Treatment Guidelines
The Centers for Disease Control and Prevention updated their sexually transmitted infections treatment guidelines with important considerations for women’s health providers, such as new recommendations for Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, pelvic inflammatory disease, and Mycoplasma genitalium.
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Does Music Lower Preoperative Anxiety in Pelvic Reconstructive Surgery Patients?
Listening to music may lower preoperative anxiety in patients undergoing pelvic reconstructive surgery.
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OB/GYN Clinical Alert Welcomes Maria F. Gallo, PhD
Maria F. Gallo, PhD, joins OB/GYN Clinical Alert. -
LMWH vs. UFH in Pregnant Women Undergoing Anticoagulation
In this retrospective cohort study of pregnant women treated with low-molecular-weight heparin (LMWH) alone compared to those switched to unfractionated heparin (UFH) in the peripartum period, the outcomes were similar in both groups.
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Evaluation and Treatment of Women with Symptoms of Recurrent UTIs
Only 33% of women presenting to a urogynecology practice with symptoms of recurrent urinary tract infections met diagnostic criteria for recurrent urinary tract infections. The use of preventive strategies can be improved.
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Ketamine Use in the Prevention of Postpartum Depression Is Premature
A double-blinded, randomized clinical trial of 134 low-risk pregnant women in Iran undergoing scheduled cesarean deliveries was conducted to address if a single dose of ketamine during anesthesia induction has a role in the prevention of postpartum depression. The authors reported that depression scores using the Edinburgh Postnatal Depression Scale at two and four weeks after the cesarean delivery were significantly lower in the ketamine group vs. the control group.
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Is Black Race Associated with Major Depression Following Early Pregnancy Loss?
Reporting symptoms of having major depression one month after treatment for early pregnancy loss was about twice as common among Black women compared to non-Black women.
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Disease Severity and Perinatal Outcomes of Pregnant Patients with COVID-19
In this observational cohort study of patients with singleton gestation and positive coronavirus test, patients with severe or critical disease were at risk for perinatal complications compared to those who were asymptomatic. Patients classified with mild or moderate disease were not shown to have an increased risk compared to asymptomatic positive patients.
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Standard-Dose vs. High-Dose Oxytocin for Labor Augmentation
In this randomized clinical trial of standard-dose vs. high-dose oxytocin regimens for labor augmentation among 1,003 nulliparous women, the primary outcome (cesarean delivery) was similar between the two groups. However, secondary outcomes were lower, labor duration was shorter, and umbilical artery acidemia occurred less frequently.