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The authors investigated invasive breast cancer incidence and mortality after a total follow-up of 11 years among the 16,608 postmenopausal women aged 50-79 years with no prior hysterectomy who were randomized to combined oral conjugated equine estrogens (0.625 mg/day) plus medroxyprogesterone acetate (2.5 mg/day) or placebo in the Women's Health Initiative (WHI) HRT study. In the initial reports from the WHI HRT study, breast cancer incidence was increased (hazard rate [HR], 1.26; 95% confidence interval [CI], 1.00-1.59).
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For many years we have been pushing the concept that the earlier that prenatal care is initiated, the better will be the outcome. Since there are certainly data proving that late enrollment makes for worse outcomes, this "the-earlier-the-better" mantra has almost attained bumper sticker status.
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It seems that at least twice a week we either inadvertently find, or have a pregnant patient referred with a band-like structure that runs north-to-south between the uterine walls. In a non-pregnant uterus this would be called a synechium, but the most common label assigned to this finding in pregnancy is a "sheet."
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A study group of 98 patients were enrolled through seven centers to evaluate the efficacy of sildenafil in the treatment of sexual dysfunction associated with the use of selective and nonselective serotonin reuptake inhibitors (SRIs).
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In this issue: Tiotropium for uncontrolled asthma, sibutramine pulled from market, incidence and mortality data from WHI, FDA Actions.
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To assess the effect of screening mammography on breast cancer mortality, the authors used data from the Norwegian Breast Cancer Screening Program to observe chronologic trends associated with screening as well as advances in breast cancer awareness and treatment.
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Patients with evidence of metastatic endometrial cancer are typically considered for surgical debulking to establish a diagnosis, reduce tumor burden, and plan adjuvant therapy.
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The authors sought to determine the accuracy of diagnosing vulvovaginal symptoms related to the three most common causes, i.e., bacterial vaginosis (BV), candidiasis vaginitis (CV), and trichomoniasis vaginalis (TV).
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Virtually every pregnant woman in the united states will have at least one ultrasound examination, and, by simple arithmetic, one-tenth of these women will have fetuses whose head circumferences (HCs) are defined as being too big (above the 95th percentile) or too small (below the 5th percentile).
