OB/GYN Clinical Alert
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Is Prenatal Screening for GBS Cost-Effective in the United States?
In this cost-effectiveness study, screening for group B streptococcus (GBS) at 36 0/7 to 37 6/7 weeks, with rescreening (if GBS results are negative after five weeks of initial screening), is the most cost-effective strategy.
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Barriers to Abortion Care and Self-Managed Abortion
In this prospective national study among people searching for abortion care online, 28% of respondents reported attempting self-managed abortion. Respondents living farther from an abortion facility and facing barriers to care were more likely to attempt self-managed abortion.
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Use of Ursodeoxycholic Acid in Pregnant Women with Obstetric Cholestasis
Ursodeoxycholic acid might be beneficial in reducing the risk of spontaneous preterm birth and meconium-stained amniotic fluid, but not stillbirths, in women with pregnancies complicated by obstetric cholestasis.
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Menopausal Hot Flashes: Can a Plant-Based Diet Provide Effective Treatment?
In this clinical trial, women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% compared to 49% in the control group over 12 weeks of observation.
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Do Women 64 to 66 Years of Age Qualify to Discontinue Cervical Screening?
These studies evaluated adherence to national guidelines for exiting from cervical cancer screening at 65 years of age and managing abnormal results on screening with human papillomavirus (HPV) and Pap co-testing and found that the majority of women 64 to 66 years of age do not qualify to discontinue screening, and the majority of women with discordant Pap and HPV test results are managed incorrectly.
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SARS-CoV-2 Infection During Pregnancy and Increased Risk of Preeclampsia
A meta-analysis of 28 observational studies found that having SARS-CoV-2 infection during pregnancy was associated with a 58% increase in the adjusted odds of having preeclampsia compared to those without SARS-CoV-2 infection during pregnancy.
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COVID-19 Vaccination, Pregnancy, Lactation, and Fertility: What Should the OB/GYN Know?
With the increasing circulation of the Delta variant, it has become critically important for the OB/GYN to discuss COVID-19 vaccination with patients, and, specifically, to address concerns related to pregnancy, lactation, and fertility. This article reviews the most recent guidance from the American College of Obstetricians and Gynecologists, the Society of Maternal-Fetal Medicine, and the American Society for Reproductive Medicine on vaccination in reproductive-age individuals.
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Vaginal Misoprostol vs. Prostaglandin E2 Pessary for Induction of Labor at Term
In this randomized, noninferiority, clinical trial of pregnant women who underwent induction of labor with misoprostol compared to dinoprostone, the rate of vaginal delivery within 24 hours was higher in the misoprostol group. Maternal satisfaction, assessed by a visual analog scale, also was higher. Although the noninferiority of dinoprostone to misoprostol could not be demonstrated, the clinical risk-to-benefit ratio justifies the use of both drugs.
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Highlights from the CDC’s Updated 2021 Sexually Transmitted Infections Treatment Guidelines
The Centers for Disease Control and Prevention updated their sexually transmitted infections treatment guidelines with important considerations for women’s health providers, such as new recommendations for Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, pelvic inflammatory disease, and Mycoplasma genitalium.
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Does Music Lower Preoperative Anxiety in Pelvic Reconstructive Surgery Patients?
Listening to music may lower preoperative anxiety in patients undergoing pelvic reconstructive surgery.