OB/GYN Clinical Alert
RSSArticles
-
Endometrial Cancer: An Update to Classification Using Molecular Features
The classification of endometrial cancer is evolving, transitioning from histological subtypes to molecular profiling. Four key molecular subtypes (POLE ultramutated, MSI unstable, p53 mutant, and NSMP) guide prognosis and treatment. The integration of molecular features into staging highlights their clinical relevance for improving diagnostic accuracy and therapeutic strategies.
-
Adverse Outcome Predictors in Pregnancies Complicated by SLE
A prior history of lupus nephritis, active systemic lupus erythematosus (SLE) at conception, secondary antiphospholipid syndrome, and chronic hypertension are critical predictors of adverse pregnancy outcomes in women with SLE.
-
Twelve-Month Contraceptive Prescriptions: Do They Make a Difference?
In this national retrospective cohort study of patients on Medicaid, states with 12-month hormonal contraceptive supply policies increased their 12-month dispensing by only 4.39% compared to the pre-policy period. The majority of this increase was contributed by the state of California.
-
Individualizing Opioid Prescriptions After Cesarean Delivery
A multicenter, randomized controlled trial of 5,521 participants who underwent uncomplicated cesarean deliveries found that an individualized opioid prescription protocol (IOPP) with shared decision-making was noninferior to a fixed prescription regarding the proportion of participants experiencing moderate to severe pain one week post-discharge, while significantly reducing the number of opioid tablets prescribed at discharge (median of 14 tablets vs. 20 tablets, P < 0.001).
-
Eat Your Fruits and Veggies to Decrease HPV Infection
The authors of a study theorized that the increase in vitamin C and other immunological benefits of a regular diet including dark green vegetables and beans and fruits may reduce inflammation and enhance the immune system response, facilitating clearance of genital human papillomavirus.
-
Immediate vs. Delayed Postpartum Long-Acting Reversible Contraception
Administering long-acting reversible contraceptives before hospital discharge reduced pregnancy risk and increased usage at six months, making it an effective option for postpartum contraception.
-
Are Deep Contraceptive Implant Removals Predictable?
In this retrospective cohort study of 747 patients undergoing contraceptive implant removal, lower body mass index at insertion, weight gain during use, and longer duration of use were risk factors for deep contraceptive implant removal procedures.
-
HPV Vaccination Disparities Among Adult Women in the United States
A longitudinal, cross-sectional cohort study of 113,344 participants demonstrated that lack of health insurance, lack of stable employment, and lower income were significantly associated with decreased human papillomavirus vaccination uptake in women aged 18-47 years residing in the United States.
-
Placenta Accreta Spectrum Among Patients Seeking Abortion
Placenta accreta spectrum (PAS) in patients seeking abortions poses significant risks, especially for those with prior cesarean deliveries. PAS, often related to prior cesarean deliveries, increases abortion-related complications. Ultrasound is key for detection, but access to skilled care may be limited because of state-based abortion restrictions, leading to worse outcomes for affected patients.
-
Malpositioned IUDs: How Easy Are They to Remove?
In this retrospective cohort study of 436 malpositioned intrauterine devices (IUDs), of the 281 that underwent removal, 82% were removed on the first attempt and 73% were removed using only ring forceps. Most embedded and partially perforated IUDs also were removed using only ring forceps (59% and 67%, respectively).