This is a two-part article on the treatment of massive hemorrhage, which is something that can be seen in any emergency department, small or large, rural or urban. There have been recent changes in the use of blood and adjuvant therapies, in part from our military advances. These articles will review the current recommendations for massive transfusion. Part II of the article will review adjunct therapies, scoring systems, and complications of massive transfusion.
Current trials with amyloid antibodies have not shown clinical benefit, but the results suggest that treating patients earlier in the course, or during the presymptomatic period, might be beneficial.
This paper summarizes and focuses on the National General Practice Study of Epilepsy with emphasis on epilepsy prognosis after initial diagnosis.
Novel protocols with functional MRI may allow clinicians to determine if some unresponsive patients are able to hear, understand, and respond to questions.