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In young children with myasthenia gravis, height and bone age are negatively impacted by chronic corticosteroid usage, but not by thymectomy.
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Utilization of continuous EEG monitoring in mechanically ventilated patients in the ICU was associated with a reduction in hospital mortality without significantly affecting hospital costs or length of stay.
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Inhaled apomorphine, at doses up to 0.8 mg, appears safe and well tolerated by patients with Parkinson's disease, but does not result in significant improvement in wearing "off" periods, at the tested doses.
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This 12-week, randomized, double-blind, placebo-controlled trial examined the combination of oxycodone and naloxone for treatment of severe restless legs syndrome in patients inadequately controlled by previous treatment.
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Rocky Mountain spotted fever is most common in the southeastern United States despite its name. It presents with headache, fever, myalgias, and a vasculitic rash that may involve the palms and soles.
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In this 12-week, randomized, double-blind and double-dummy trial, intrajejunal infusion of levodopa-carbidopa gel decreased "off" time by almost 2 hours more than oral levodopa-carbidopa in individuals with Parkinson's disease suffering motor fluctuations.
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Although never confirmed in a randomized clinical trial, thymectomy appears to be efficacious in children with antibody-positive myasthenia gravis.
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