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The past few years have seen a number of emerging household toxins, novel antidotes, and new prescription drugs on which to overdose. The following article reviews the latest updates in medical toxicology, with a focus on accidental exposures and drug overdoses as they pertain to the practicing emergency physician.
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Osteoarthritis (OA) can be described as the failed repair of damage that has been caused by excessive mechanical stress (defined as force/unit area) on joint tissues.1 This implies that although multiple factors may lead to OA, mechanical impact (either as a major single event or as repetitive micro trauma) is central to all of these, and that the sequence of events that ensues represents the intrinsic repair process, which may either fail or be successful in restoring joint function. Also known as osteoarthrosis or degenerative joint disease, OA is the most important chronic musculoskeletal disorder in both humans and horses.
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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Treatment and Outcome after Acute Cervical Artery Occlusion with Stroke; Continuous Transcranial Doppler Insonation Can Determine Recanalization Following Acute Ischemic Stroke; Antithrombotic Therapy Appears to be Safe for Patients with Cerebral Cavernous Malformations
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Interpret the lead MCL-1 rhythm strip shown in the figure. Does this rhythm represent Mobitz I (Wenckebach) or Mobitz II AV block? Is a pacemaker likely to be needed?
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Evidence-based updates in primary care medicine By Louis Kuritzky, MD
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In men taking oral fluoroquinolone antibiotics, the risk of acute renal failure is doubled, and when combined with renin-angiotensin-system blockers, the risk increases by 4.5 fold.
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This large, multicenter, quality improvement project showed a dramatic reduction in mortality among patients with severe sepsis or septic shock after implementation of a sepsis treatment bundle.
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Medications for Risk Reduction of Breast Cancer in Women
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Primary percutaneous coronary intervention (PCI) is the preferred strategy for treating ST-segment elevation myocardial infarction (STEMI).