Neurology
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Public Health Interventions to Reduce COVID-19 Spread
After studying the association of public health interventions with the epidemiological features of the COVID-19 outbreak in Wuhan, China, the authors found nonpharmaceutical interventions may be associated with better outbreak control.
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Expansion and Versatility of Telemedicine During the COVID-19 Pandemic
Telemedicine has rapidly transformed healthcare delivery during the COVID-19 pandemic, but innovative reimbursement models and updated privacy regulations are needed to ensure widespread implementation of high-quality digital care.
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Two Possible Mechanisms of Disease in COVID-19
COVID-19 infection may be associated with an increased risk of blood clotting and related thrombotic events, but there are insufficient data to support indiscriminately discontinuing medications that play a critical role in the management of chronic cardiovascular disease.
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Guillain-Barré, Miller Fisher Syndrome, and Associated Disorders in Patients with COVID-19
As the COVID-19 pandemic spreads around the world, investigators in multiple countries are reporting patients with myriad cranial and peripheral nerve disorders that have some, but not all, features of Guillain-Barré syndrome.
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The Effect of Coronaviruses on the Central Nervous System
Known coronaviruses can enter the central nervous system by different pathophysiologic mechanisms. Neurological presentations linked to the novel SARS-CoV-2 include encephalopathy, encephalitis, cranial neuropathies, Guillain-Barré syndrome and other neuropathies, and ischemic and hemorrhagic strokes.
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Neurologic Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China
Neurological symptoms and impairments have been found in one-third of hospitalized patients with COVID-19 from countries that have reported these observations so far. This is a rapidly evolving consequence of SARS-CoV-2 infection.
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Tucatinib Tablets (Tukysa)
Tucatinib should be prescribed in combination with trastuzumab and capecitabine to treat adults with advanced unresectable or metastatic HER2-positive breast cancer.
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women.
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Heart Failure Confers Increased Risk of Venous Thromboembolic Events
In the Atherosclerosis Risk in Communities (ARIC) cohort, incident heart failure hospitalization with either preserved or reduced ejection fraction was associated with long-term increased risk of venous thromboembolic events.
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For Knee Arthritis: Physical Therapy or the Needle?
In a small, randomized, controlled trial of patients with knee osteoarthritis, those who received physical therapy reported less pain and functional disability at one year than those who received one or more glucocorticoid intra-articular injections.