Neurology
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Dermatomyositis Sine Dermatitis Is an Important Clinical Entity
Dermatomyositis is an autoimmune disorder of skeletal muscle associated with a variety of auto-antibodies and specific muscle pathology but it may not have a skin rash. Muscle pathology and antibody determinations are important for accurate diagnosis and treatment.
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Randomized Diagnostic Trial of First-Line Genome Sequencing in Pediatric White Matter Disorders
The results of this study indicate that first-line genome sequencing in pediatric patients with suspected genetic white matter disease is more diagnostically efficient, defined as higher diagnostic efficacy and shorter time to diagnosis, than current standard of care approaches.
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Plasma Phospho-Tau217 Is a Promising Alzheimer’s Disease Biomarker
Validation and replication of findings in the use of the blood biomarker phospho-tau 217 for the diagnosis of Alzheimer’s disease holds out the possibility for a new era in the early diagnosis and treatment of this debilitating illness.
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Scientists Observe Possible Relationship Between Autism Subtype, Cholesterol Levels
Results of this investigation confirm the challenges of understanding autism, its subtypes, and the arcane causes.
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Is It Dizziness or Dementia?
Researchers find certain systolic blood pressure changes may be connected with higher risk for dementia.
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Decitabine and Cedazuridine Tablets (Inqovi)
Inqovi should be prescribed to treat adults with myelodysplastic syndromes.
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Cheyne-Stokes Respiration in Heart Failure
A comprehensive cardiorespiratory study of stable systolic heart failure patients showed Cheyne-Stokes breathing in the awake, upright position is related to hypercapnia and is independently associated with a higher risk of cardiac death.
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Risks of Hookah Smoking
An average hookah contains as much tobacco as 20 filtered cigarettes. The nicotine hit from a hookah is every bit as real and as addictive as smoking cigarettes. The temperature of the smoke when heated electronically in newer hookahs, rather than by older charcoal versions, may be cidal to lung cells.
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Stroke Risk: COVID-19 vs. Influenza
During the early surge in COVID-19 infections in New York City, many neurologists observed an unusual frequency of ischemic stroke. Researchers investigated further. Read on to learn what they discovered.
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The Relationship Among Step Count, Step Intensity, and Mortality in Adults
Investigators found an association between higher number of steps taken daily and lower all-cause mortality, lower mortality from cardiovascular disease, and lower mortality from cancer, but no association between intensity of steps and mortality in any of those areas.