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Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
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After results of the pivotal NINDS intravenous thrombolysis (IV rtPA) trial were published in 1995, there has been a gradual extension of the time window from 3 hours to 4.5 hours, based on additional trials (ECASS II and III).
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Chest pain presentations to the emergency department (ED) are common and very costly to the health care system. Although the event rates are low in patients with a low clinical risk profile, the price of a missed diagnosis is high.
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In this paper, the authors reviewed long-term survival data from a large population of out-of-hospital cardiac arrest patients who were discharged alive after their arrest. All patients who have a cardiac arrest in Seattle and King County, Washington, are entered into a registry organized to follow the Utstein guidelines for reporting cardiac arrest.
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In this randomized study, patients with left-sided infective endocarditis and large vegetations who underwent valve replacement surgery within 48 hours of randomization had lower rates of embolic events and death from any cause after 6 months compared to those who underwent surgery later.
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Some patients who experience stroke or transient ischemic attack (TIA) of unknown cause (i.e., cryptogenic) are subsequently found to have a patent foramen ovale (PFO).
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When fewer ICU beds were available, patients experiencing a medical emergency team call were less likely to be admitted to the ICU and more likely to have their goals of care changed.