Neurology
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Subclinical Influenza Infection in Healthcare Workers
Despite all precautions, influenza vaccination, handwashing campaigns, and messaging to staff not to come to work with respiratory symptoms, healthcare workers are an important source of nosocomial influenza and respiratory infection. Now, it is happening with COVID-19.
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Excess Deaths During COVID-19
Compared with death data for the same weeks from prior years, nearly 300,000 excess deaths occurred in the United States between the weeks ending Jan. 26 through Oct. 3, 2020. Two-thirds were attributed to COVID-19.
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Cognitive Benefit of Rivastigmine in Parkinson’s Disease Dementia with Orthostatic Hypotension
Individuals with Parkinson’s disease dementia and orthostatic hypotension (OH) showed more robust cognitive improvement from rivastigmine vs. those without OH. The anti-OH effect of rivastigmine probably mediates this better response.
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How to Record Reliable Blood Pressure Measurements
A small, community-based study to detect hypertension revealed one week of twice-daily home blood pressure (BP) measurements are more reliable and more accurately predict increased left ventricular mass than clinic or 24-hour ambulatory BP monitoring.
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Prior Metformin Use in Patients with Diabetes Hospitalized for COVID-19
Investigators found metformin use before COVID-19 hospitalization for patients with diabetes was associated with a lower risk of death.
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Why Is There Group Beating?
The ECG in the figure was obtained from a 40-year-old man with an irregular heartbeat. How would one interpret this rhythm?
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Relugolix Tablets (Orgovyx)
Relugolix should be prescribed to adults with advanced prostate cancer.
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Prophylactic PCI for Vulnerable Plaques
In this proof-of-concept trial, treatment of non-flow limiting vulnerable plaque by PCI with bioabsorbable stents resulted in no significant difference in lesion-related events compared with optimal medical therapy.
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Does MRSA Nares Colonization Predict Non-Respiratory MRSA Infections?
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) carried a high negative predictive value to rule out MRSA infections at various sites.
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Air Pollution and Cognitive Decline
In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.