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Neurology

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  • Anti-MAG or Not?

    Pure sensory clinical phenotype, low median and ulnar terminal latency index, and absence of M responses in the lower limbs were significantly associated with the diagnosis of MAG-PN, and indicate a moderate to large increase in probability of this diagnosis in patients with chronic dysimmune demyelinating polyneuropathies.
  • Extraocular Muscle Susceptibility in Neuromuscular Disease

    Extraocular muscles have fundamentally distinct structural, functional, biochemical and immunological properties compared to other skeletal muscles. While these properties enable high fatigue resistance and the rapid and precise control of extraocular motility, they might also explain why extraocular muscles are selectively involved in certain disorders, such as chronic progressive external ophthalmoplegia, myasthenia gravis, and Graves ophthalmopathy.
  • Do Autoantibodies Cause Narcolepsy?

    IgG from all narcolepsy patients significantly enhanced bladder contractile responses to the muscarinic agonist carbachol and neuronally released acetylcholine, as compared to the control IgG.
  • High Homocysteine and Stroke: Cause or Effect?

    The observed increase in risk of stroke among individuals homozygous for the MTHFR T allele is close to that predicted from the differences in homocysteine concentration conferred by this variant.
  • Pharmacology Watch: The Risk of Aspirin Withdrawal in ACS Patients

    Stopping aspirin may be hazardous to your health, according to recent research.
  • An Overview of Osteopathic Medicine: Principles and Practice

    Today, osteopathic physicians (DOs) are recognized for the unlimited practice of medicine in all 50 states, the District of Columbia, and U.S. territories. Allopathic and osteopathic physicians train and practice together in offices, hospitals, and the Armed Forces. Despite this, many physicians, as well as much of the public, are not aware of the distinctions between osteopathic and allopathic medicine. While differing in philosophy, the most noticeable difference between DOs and allopathic physicians (MDs) is the use of osteopathic manipulative treatment.
  • Full February 21, 2005, Issue in PDF

  • Food Allergy

    Recent epidemiologic studies indicate that nearly 4% of Americans are afflicted with food allergies. The spectrum of food allergy ranges from atopic dermatitis or other cutaneous manifestations hours after eating the problem food, to life-threatening events occurring shortly after ingestion. As well, some individuals experience allergic symptoms only if the food is eaten before physical stimuli such as vigorous physical exercise.
  • Pharmacology Watch: Statins and the Incidence of Rhabdomyolysis

    The most commonly prescribed statins have a low incidence of rhabdomyolysis, according to the results a new study of more than 250,000 patients.
  • ECG Review: Incomplete LBBB?

    Interpret the 12-lead ECG in the Figure, obtained from a 47-year-old man who presented with dyspnea. Is there incomplete LBBB (left bundle branch block)?