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In the past few years, new strategies in the management of sepsis have shown significant mortality benefits. This article addresses aspects regarding the management of sepsis, including appropriate fluid administration, medications, and other evidence-based strategies necessary for the treatment of septic patients in the emergency department. With the incorporation of these new practice strategies in addition to the guidelines published by the Surviving Sepsis Campaign, emergency physicians can contribute to a significant decrease in sepsis mortality in the years to come.
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Entecavir is a nucleoside analog approved for the treatment of chronic hepatitis B viremia. It has demonstrated antiviral activity against both wild-type and lamivudine-resistant virus.
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Celiac disease was found in 3.4% of patients with osteoporosis, compared to 0.2% without. Treatment with a gluten-free diet improved bone density scores. This study postulates that this prevalence justifies serologic screening for celiac disease in all patients with osteoporosis.
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Hip fractures occur 2-4 times more commonly in persons who have sustained a stroke than in an age-matched population.
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Physicians who have been practicing longer may be at risk for providing less quality care.
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Pramlintide reduces postprandial glucose excursions and oxidative stress in type 1 diabetes when given with short acting insulin at mealtime.
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NG feeding should be used for dysphagic patients early and PEG feeding reserved for those who do not tolerate NG feeding or who require long-term tube feeding.
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Screening for osteoporosis may result in fewer hip fractures.