Neurology
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Antibiotic Therapy: How Long Is Long Enough?
The CDC and the American College of Physicians have provided advice on the best practice regarding the duration of antibiotic therapy for several common infections. -
Prophylaxis for Tuberculosis in Patients with Myasthenia Gravis
In this observational study from an area with a high rate of endemic tuberculosis (TB), prophylactic treatment of TB was appropriate in those treated with high doses of prednisone and evidence of prior TB infection.
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Long-Term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Cholinesterase inhibitors are one of the few drug classes approved by the Food and Drug Administration for the treatment of patients with Alzheimer’s disease. This study shows a long-term benefit in slowing the decline of cognition, as measured by the Mini-Mental State Exam, but it is unclear if there is any benefit in quality of life.
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Genetic Biomarkers of Immunoglobulin Response in Patients with CIDP
Nearly 25% of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) have a poor response to intravenous immunoglobulin treatment. Variations in the PRF1 and FCGR2B genes in CIDP patients offer insights into the heterogenous treatment response.
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Association of Sleepwalking and REM Sleep Behavior Disorder in Men with Parkinson’s
In this retrospective, cross-sectional study of men, both sleepwalking and rapid eye movement sleep behavior disorder were associated with the development of Parkinson’s disease.
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Effectiveness of Bariatric Surgery for the Treatment of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension is an important cause of intractable headaches and may cause permanent loss of vision as a result of chronic papilledema. Weight loss is an effective treatment, and this randomized study demonstrated superior outcomes for both weight loss and reduced intracranial pressure from bariatric surgery compared to community weight-loss programs.
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Drospirenone and Estetrol Tablets (Nextstellis)
Nextstellis can be prescribed to women of reproductive potential to prevent pregnancy.
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Vitamin D and COVID-19
Low levels of vitamin D are associated with in-hospital mortality in patients with COVID-19, but causality is unknown.
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Dairy, Bone Health, and Menopause
An analysis of data from the Study of Women’s Health Across the Nation cohort did not reveal a significant association between daily dairy intake frequency, femoral and spine bone mineral density loss, and non-traumatic fracture risk among women transitioning to menopause.
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Giving the Cold Shoulder to Drug Therapy for Atrial Fibrillation
In two randomized trials published simultaneously, cryoballoon ablation proved superior to drug therapy for prevention of arrhythmia recurrence in patients with paroxysmal atrial fibrillation.