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In addition to previously identified antibodies that cause limbic encephalitis, novel antibodies directed against cell membrane antigens may cause many of the "antibody-negative" cases, and these cases seem to respond favorably to immunosuppressive treatment.
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Although spontaneous intracranial hypotension (SIH) generally causes a benign, self-limited, postural headache, subdural hematomas may occur in SIH with serious sequelae.
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Compared with a lower dose, intensive treatment with atorvastatin in patients with stable coronary disease significantly reduces hospitalizations for HF.
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Current AP schedules do not appear to prevent catheter-related thrombosis. Systemic VTE and mortality, however, appeared lower after prophylaxis.
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Elimination of daily routine CXRs reduced the number of CXRs in a mixed medical-surgical ICU, while not affecting readmission rate and ICU and hospital mortality rates.
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Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.
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In the institution in which this study took place, an audit revealed that adherence to 9 ICU protocols ranged from 62% to 77%. The protocols focused on a variety of patient care needs including sedation/analgesia, DVT prophylaxis, enteral nutrition, insulin administration, skin care, stress ulcer prophylaxis, and ventilator weaning.
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Building on the results of previous pilot studies from their laboratory and a meta-analysis that showed a tendency toward improved mortality in critically-ill patients following selenium administration, Angstwurm and colleagues used a randomized, placebo-controlled multi-center trial to determine whether intravenous administration of selenium could improve outcomes in severe sepsis and septic shock.
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