Neurology
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Inclisiran Injection (Leqvio)
Inclisiran can be prescribed as an adjunct to diet and maximally tolerated statin therapy for adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who required additional low-density lipoprotein cholesterol lowering.
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Adverse Effects of Electronic Cigarettes on the Disease-Naïve Oral Microbiome
A robust metagenomic comparison study of the effects of electronic cigarettes on oral microbiomes suggested that the unique aerosol component of electronic cigarettes poses increased risk to development of oral cavity disease.
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Plant-Based Diets and Menopausal Hot Flashes
Women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% vs. 49% in the control group over 12 weeks of observation.
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Infections Before Age 20 Years Increase the Risk of Multiple Sclerosis
Researchers found patients diagnosed with infection in adolescence were at higher risk for multiple sclerosis, even after exclusion of infectious mononucleosis, pneumonia, and central nervous system infection.
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New Dietary Guidance to Improve Cardiovascular Health: Meeting People Where They Are
The American Heart Association emphasizes the importance of an overall lifetime heart-healthy diet and the vital role of nutrition early in life.
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Clinicians’ Confusion over Brain Death Criteria Persists
There are inconsistencies between standards and institutional protocols and clinical practice. Inconsistencies can erode clinician and public trust in the determination of death by neurologic criteria. Inconsistencies also can cause false-positive determinations in which a patient is incorrectly determined to be dead. Ethicists should advocate for ensuring clinicians involved in the determination of death by neurologic criteria are equipped with appropriate expertise.
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Heart Health and Cognitive Decline: Who Fares Better?
More middle-age men might be living with various cardiovascular risk factors and diseases, but the associated negative effects on cognition could be worse for women of the same age with the same conditions.
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National Alzheimer’s Plan Updated with New Focus on Healthy Aging
Feds add sixth goal in the ninth version of this annually released report.
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Stroke Patients Visit EDs Often After Discharge from Hospital
Repeat visits to the ED are quite common, even for patients who experienced mild or moderate strokes and are managing their conditions at home. This suggests home care models for these complex patients are important to evaluate and modify, if needed, to improve long-term care outcomes.
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Post-Exercise Premature Ventricular Contraction, or Aberrancy?
The ECG in the figure is a post-exercise tracing. There are four wider and slightly early occurring beats in the long lead rhythm strips. Are these beats premature ventricular contractions or premature atrial contractions conducted with aberration?