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Overall, clopidogrel plus aspirin was not significantly more effective than aspirin alone in reducing the rate of myocardial infarction, stroke, or death from cardiovascular disease.
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A new agent with a unique mechanism of action has been approved for the treatment of chronic constipation.
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FDA Recommends Approval of Muraglitazar, But May Need To Reconsider; Which Antipsychotics Are More Dangerous?; Should CPOE Undergo Evaluation?; New Treatment for Tennis Elbow; FDA Actions
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Fabry disease must be considered in all cases of unexplained stroke in young patients, especially in those with the combination of infarction in the vertebrobasilar artery system and proteinuria.
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In patients with an ischemic stroke, a normal carotid DUS examination does not support the routine use of TEE to exclude the presence of complex aortic arch plaque or thrombi.
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Patent foramen ovale is commonly associated with cryptogenic stroke, but there is inadequate evidence in the medical literature to support the use of transcatheter closure devices ...
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A long term placebo controlled study is now needed to establish whether cannabinoids may have a role beyond symptom amelioration in MS.
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Modafinil failed to significantly improve EDS in PD compared with placebo.
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A small but significant number of patients with unrecognized ALS undergo spinal surgery that in retrospect may be inappropriate.