Neurology
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Delaying Antibiotics in Patients with Suspected Infection Increases Risk of Septic Shock
A retrospective cohort study revealed delaying the first dose of antibiotics in patients suspected of presenting with an infection in the ED led to a higher risk of progressing to septic shock and in-hospital mortality. Every hour antibiotics were delayed raised the risk of septic shock by 4%.
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How Certain is a Negative Echocardiogram for Excluding Infective Endocarditis?
Applying the proposed strict negative criteria for infective endocarditis (IE) on the first echocardiogram indicated this approach largely prevented unnecessary repeat tests unless clinically indicated for continued suspicion of IE.
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Yoga for the Mind, Body, and Autonomic Nervous System
Randomization to yoga in addition to standard care to treat vasovagal syncope led to better outcomes than standard care alone, with reductions in syncopal and presyncopal events and improvement in quality of life scores at one year.
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Finding the Most Effective Treatment for Hair Loss in Men
Among three common treatments for male androgenic alopecia, the authors of a meta-analysis found 0.5 mg/day of dutasteride to be the most effective.
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Neurologists Add Nuance to Palliative Care Definition
Position paper authors underscore the importance of care goals discussions with patients and families throughout the disease course, not just at end of life.
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Many Parkinson’s Research Participants Cannot Recall Study Risks
Rather than consenting an individual in the office during the presurgical visit, at a time when the patient was already receiving a large amount of information, the outreach could be conducted by phone later. This would give the subject time to carefully review the study materials.
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Updated Guidance on Informed Consent in Stroke Management
A new position statement aims to help neurologists provide the highest quality patient care for ischemic stroke by providing ethical guidance on how to navigate the decision-making process for stroke patients who may struggle to provide consent.
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Bebtelovimab Injection
The FDA has issued an emergency use authorization for a monoclonal antibody that demonstrated efficacy against the omicron variant of COVID-19.
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VIRSTA vs. PREDICT: Which Is Best for Anticipating Endocarditis?
Researchers in Columbia put predictive scoring methods through their paces.
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Importance of Exercise Testing-Associated Ventricular Ectopy
A study of asymptomatic subjects without known cardiovascular disease undergoing treadmill exercise testing and followed for a mean of 20 years showed high-grade premature ventricular contractions during exercise recovery (but not during exercise) are predictive of subsequent cardiovascular mortality.