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Cases of autopsy-proven corticobasal degeneration examined in a U.S. academic center presented with frontal-predominant behavioral or cognitive deficits, with a movement disorder following later in the majority.
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Two recent clinical trials, rocket af and aristotle, have added two new direct thrombin inhibitors, in addition to dabigatran (RE-LY), to our armamentarium to prevent stroke in patients with atrial fibrillation.
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Medication poisonings in children; rosuvastatin vs atorvastatin for atherosclerosis; saw palmetto for prostate symptoms; using atypical antipsychotics for off-label indications in adults; and FDA actions.
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Extracorporeal membrane oxygenation is associated with a high mortality and a high incidence of neurological complications including stroke, subarachnoid hemorrhage, and brain death.
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This issue might be subtitled "What will they think of next?" Getting high does not always require the purchase of illegal drugs, and all substances that alter sensorium, such as nutmeg, cannot be regulated. However, the emergency physician must remain aware of the latest fads of drug abuse, and should be able to recognize the symptoms they cause.
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A program that sends geriatricians and nurse practitioners into the homes of high-risk, frail elderly patients has resulted in a 195% return on investment (ROI) for Fallon Community Health Plan in Worcester, MA.