Neurology
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The Economic Burden of Undiagnosed Pre-diabetes
The economic burden of diagnosed and undiagnosed diabetes, gestational diabetes, and prediabetes has exceeded $322 billion.
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Treatment of C. Difficile — Follow the Guidelines
ABSTRACT & COMMENTARY: The primary outcome was the occurrence of complications, including relapse within four weeks, surgery, and 30-day mortality.
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Should Clinicians Discuss Resumption of Sexual Activity Following an Acute MI?
Although the U.S. and European cardiovascular society guidelines recommend that patients be counseled about resuming sexual activity after suffering an acute myocardial infarction (AMI), the actual demographics of sexual education post-myocardial infarction (MI) are unknown.
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Statins and the Neuromuscular System
Statins inhibit the function of 3-hydroy-3-methylglutaryl coenzyme A reductase and are widely used for risk reduction of cardiovascular and cerebrovascular disease. It is estimated that about 10% of patients will discontinue statins due to muscle-related symptoms.
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Predicting Efficacy of IVIG in CIDP
In a retrospective chart review of 281 treatment-naïve patients with chronic inflammatory demyelinating polyradiculoneuropathy, lack of response to intravenous immunoglobulin was predicted by 1) presence of painful neuropathy and 2) strength differences between arm and leg muscles.
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Progesterone in Acute Traumatic Brain Injury
ABSTRACT & COMMENTARY: Administration of progesterone after acute traumatic brain injury does not improve neurological outcome nor reduce mortality.
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The Clinical Spectrum of Encephalitis
Encephalitis is a serious neurologic condition caused by acute inflammation of the brain. Patients typically present acutely with any combination of confusion, fever, seizures, headache, focal neurologic deficits, and abnormal involuntary movements. Diagnosis is typically made by cerebrospinal fluid (CSF) analysis and serologic studies on CSF and blood.
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Can Answering a Phone Call Give You Cancer?
In the past decade, cellular phone usage has grown exponentially worldwide, and this use is prevalent in all age groups, including children.
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Clinical Practice Guidelines for Platelet Transfusion
The American Association of Blood Banks has six recommendations of varying strengths based on the availability of quality evidence.
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Intracranial Hemorrhage Risk: Are Novel Oral Anticoagulants Better Than Warfarin?
Clinicians have commonly overestimated the risk of intracerebral hemorrhage (ICH) during anticoagulant therapy. Indeed, such misapprehensions have sometimes led to failure to employ warfarin (and probably other agents) when indicated for atrial fibrillation. There is little dispute that novel oral anticoagulants (apixiban, dabigatran, rivaroxaban) are simpler to use, since they do not require monitoring and are essentially free of food interactions. Clinical trials with novel oral anticoagulants (NOACs) have consistently documented that NOACs are associated with lesser risk of ICH, which is certainly a good thing … but how much of a good thing?