Neurology
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Hypothermia after Acute Traumatic Brain Injury Revisited
Hypothermia therapy is effective after severe traumatic brain injury for patients ages 50 years and younger. However, mortality was increased in patients treated with hypothermia who had diffuse injury with swelling on CT.
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Is Early MRI Warranted for Back Pain in the Elderly?
In an analysis of a large dataset from several large integrated health care systems of patients older than 65 years of age with new-onset low back pain, early spine imaging did not alter management or outcomes, but added considerable cost to their care.
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Does Traumatic Brain Injury Cause Sleep Disruption?
In a well-designed animal model of traumatic brain injury, a sleep disorder was induced that resembles, in many ways, what is observed in spontaneous human narcolepsy.
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Relationship Between Brain MRI Biomarkers and Cognition
In a prospective, longitudinal, cohort study of an asymptomatic, multi-ethnic Dallas community, brain MRI biomarkers measuring volume were associated with cognitive functions, as measured by the Montreal Cognitive Assessment.
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Neurologic Disease and Criminal Behavior – A Medicolegal Conundrum
Patients with frontotemporal dementia, primary progressive aphasia, and Huntington’s disease exhibited antisocial and/or criminal behavior.
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Clinical Briefs
Clinical Briefs on topics such as: Chronobiology and Insulin Glargine, Dual Add-on Therapy for Type 2 Diabetes When Metformin is Not Enough, and Might Long-term Dual Antiplatelet Therapy Be Better? Not
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Are Atrial Premature Complexes Benign?
Atrial premature complexes (APCs) are commonly observed on routine ECGs and believed to be harbingers of atrial fibrillation, especially in patients with cardiovascular disease. However, little is known about the long-term prognosis of APCs in the general population. Thus, these investigators from Japan analyzed the database of a large community-based cohort from 1993 to 2008 to determine the risks of APCs seen on the subjects’ baseline ECGs.
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Statins After an MI: Does it Happen?
Following a hospitalization for coronary heart disease (CHD) or acute coronary syndrome (ACS), randomized trials demonstrate that high-intensity atorvastatin is more effective than either placebo or low- to moderate-intensity therapy with either pravastatin or atorvastatin.1-3 Based on this evidence, the American College of Cardiology and the American Heart Association guidelines recommend high-intensity therapy in cases of an acute cardiac event and that therapy be initiated before discharge.
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Is it Worth it? Do “Healthy” Dietary Guidelines Lower the Risk of Heart Disease?
Recent controversy surrounds diet and its impact on cardiovascular disease (CVD). In this study, Reidlinger and her colleagues sought to assess diet by comparing the effects on vascular and lipid CVD risk factors of adhering to a diet consistent with United Kingdom (UK) dietary guidelines (DG group) to a traditional British diet (control group).
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Another Reason to Recommend Smoking Cessation
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, affecting an estimated 2.7 million individuals in the United States.1 The proportion of strokes attributable to AF increases strikingly from 1.5% at 50-59 years of age to 23.5% at 80-89 years of age.2 Approximately 15-20% of all strokes are due to AF. To predict the thromboembolic risk in the individual patient, risk models used most frequently are CHA2DS2-VASc and CHADS2 scores. The CHA2DS2-VASc score may be the better option since both the 2014 American Heart Association, American College of Cardiology, Heart Rhythm Society AF guidelines, and the 2012 European Society of Cardiology AF guidelines prefer it when evaluating the individual thromboembolic risk associated with AF and to determine the risk:benefit ratio of antithrombotic therapy.3