Neurology
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Idarucizumab: A Promising New Drug that Reverses the Anticoagulant Effects of Dabigatran
A recent study found that idarucizumab rapidly reverses the effects of dabigatran and is likely to have important clinical benefits for patients with intracerebral hemorrhage and other disease processes in which reversal of anticoagulation is important.
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Clinical Briefs
In this section: Reconsidering the value of oral nutritional supplementation in patients admitted for COPD; recognizing a relationship between asthma and obesity; and weighing the benefits of sound stimulation in Alzheimer's patients.
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Eluxadoline Tablets (Viberzi) and Rifaximin (Xifaxan) Tablets
Both drugs appear to provide modest benefit in irritable bowel syndrome with diarrhea.
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Statin Use and Cognitive Effects: Not a Brain Drain
A meta-analysis of data from more than 28,000 patients enrolled in 18 randomized, placebo-controlled trials of statin therapy failed to show a causal relationship between treatment and adverse neurocognitive effects for patients with and without cognitive impairment.
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Prostate Cancer and Smoking: One More Reason to Trash the Tobacco
Study showed that following prostatectomy for cancer, smokers and ex-smokers had a higher risk of recurrence.
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You Are What You Feed Your Gut Microbiome
There is mounting evidence that the gut microbiome influences the immune system and the central and peripheral nervous systems.
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ECG Review: What are the Clinical Implications of this Rhythm?
This tracing was obtained from a 69-year-old woman with a long-term history of palpitations. Her symptoms had been increasing over recent weeks, in association with “chest tightness” and dizziness. Her prior medical history was benign, and she was hemodynamically stable at the time this tracing was recorded. How would you interpret this rhythm strip? What are the clinical implications of this rhythm?
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Clinical Briefs
A closer look at non-alcoholic fatty liver disease, lifting the ban on total dietary fat, and the risks of digoxin use in AF patients.
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Cholic Acid Capsules (Cholbam ®)
The cholic acid capsule is the first FDA-approved treatment for rare bile acid synthesis disorders.
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Inferior Vena Cava Filters and Recurrent Pulmonary Embolism
Placement of retrievable inferior vena cava filters in individuals with concurrent deep vein thrombosis does not reduce the risk of recurrent pulmonary embolism.