Neurology
RSSArticles
-
Why Dentists Are Suddenly Smiling
In this meta-analysis of 51 randomized, controlled studies that included nearly 5000 patients, continuous positive airway pressure and oral appliances resulted in comparable and statistically significant reductions in blood pressure.
-
Diabetes, Dementia, and Hormones
Higher levels of estrogen may exacerbate risks that type 2 diabetes pose for cognitive function decline in older women.
-
Delay in Performing Endovascular Reperfusion Results in Worse Disability Outcomes
In the past year, multiple clinical trials have reported that intra-arterial endovascular reperfusion with mechanical clot extraction, using the SOLITAIRE stent retriever device and others, results in better neurological outcomes than treating patients with intravenous thrombolysis alone with TPA. There is still uncertainty regarding the maximum time window, and how important early intervention is as related to neurological recovery and long-term outcomes.
-
Spironolactone for Resistant Hypertension
Resistant hypertension is common, and the choice of additional drug therapy in this condition is not clear.
-
Clinicians Are Skeptical of Early Warning Systems for Sepsis
Severe sepsis is very common, with high morbidity and mortality. Early recognition and intervention improves mortality. However, the diagnosis may often be missed in early sepsis. An academic health system developed an electronic early warning and response system for sepsis in 2012, monitoring real time vital signs and laboratory data for hospitalized, non-ICU, acute care patients and notifying clinicians when specific criteria were met. -
Bedside Ultrasound: Is It a Reliable Tool for Guiding Resuscitation in Patients with Undifferentiated Hypotension?
The use of bedside ultrasound has expanded tremendously over the last few decades. As it is readily available and relatively inexpensive, ultrasound provides the opportunity to examine hypotensive, critically ill patients, potentially leading to a faster, more accurate diagnosis.
-
Sepsis Resuscitation and Mortality
The use of balanced salt solutions rather than isotonic saline or colloids may improve in-hospital mortality in patients admitted with septic shock.
-
Optimal Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke
This study strongly suggests that compared with maintaining patients on aspirin alone, switching to a different antiplatelet agent, or adding a second antiplatelet agent to aspirin may be better in preventing subsequent vascular events in patients who experienced a new ischemic stroke while taking aspirin.
-
Treatment of AVM-related Epilepsy
There is insufficient evidence to recommend invasive AVM management to reduce epileptic seizure frequency, and this will have to be evaluated in a long-term randomized, controlled clinical trial.
-
ICH May Clinically Mimic TIA
In a large retrospective review of 2137 patients with intracerebral hemorrhage, 34 had transient symptoms that could have been misclassified as “transient ischemic attack” if brain imaging had not been performed.