Neurology
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A Brief Report of Clinical Trials Results from the 2016 International Stroke Conference
This article provides an overview of the research presented at the 2016 International Stroke Conference.
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Hypoxia-induced Migraine
Hypoxia-induced migraine attacks with and without aura, in an experimental paradigm, were accompanied by dilation of cranial arteries in individuals who have migraine with aura, as well as in healthy control subjects.
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Predicting Seizure Recurrence with Routine EEG after First Unprovoked Seizure
The authors systematically reviewed prospective and retrospective studies of adults and children undergoing routine electroencephalography (EEG) after a first unprovoked seizure who were followed for at least 1 year. Using positive likelihood ratios, an adult and child with epileptiform discharges on EEG were estimated to have a 77% and 66% probability, respectively, of recurrent seizures.
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Pick Disease: Picking Away at the Pathology
The neuropathologic changes of Pick disease may sequentially progress through the brain in specified phases over time and may correlate with the progression of clinical symptoms.
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Thalamic Pain: Who Is Likely to Develop This Disorder?
In a careful anatomic and physiologic study of patients with thalamic stroke, the authors demonstrated that the combination of anterior pulvinar nucleus involvement with spinothalamic dysfunction predicts a “thalamic pain syndrome” with > 90% sensitivity.
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Peripheral Nerve Disorders After Cardiac Surgery
Following cardiac surgery, about 6% of patients will suffer a peripheral nerve injury, mostly due to compression, traction, or nerve ischemia. Proper patient positioning can prevent most of these injuries.
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Treatment of Acute Ischemic Stroke
MONOGRAPH: The faster definitive stroke treatment is administered, the better the outcomes. Unfortunately, most patients arrive too late.
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Clinical Briefs
In this section: a better way to measure blood pressure; the magical powers of grapefruit juice; and yet another reason to stop smoking.
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Coagulation Factor IX (Recombinant), Albumin Fusion Protein
This product is indicated for on-demand control and prevention of bleeding episodes, perioperative management of bleeding, or routine prophylaxis to prevent or reduce the frequency of bleeding episodes in children and adults with hemophilia B (congenital factor IX deficiency).
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Prescient Warning Symptoms: A New Target for Sudden Cardiac Death Prevention
Typical cardiac symptoms frequently precede sudden cardiac arrest and are frequently unheeded, but when acted on are associated with decreased mortality.