Neurology
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Trimethoprim-sulfamethoxazole vs. Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized, clinical trial found that a seven-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo.
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Association of Seafood Consumption and Brain Mercury Levels with Brain Neuropathology
Although moderate seafood consumption was correlated with higher brain levels of mercury, these levels were not correlated with brain neuropathology.
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Intracerebral Hemorrhages Associated with Non-vitamin K Oral Anticoagulants Appear to Be Smaller than Those Associated with Warfarin
Intracerebral hemorrhage is the most dangerous complication of treatment with oral anticoagulants, and this complication carries a high mortality. Because of the increasing prevalence of atrial fibrillation in the elderly population, and the increasing use of oral anticoagulants, the overall prevalence of intracerebral hemorrhage is increasing.
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Optimal Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke
Patients presenting with acute ischemic stroke are often taking aspirin on a regular basis for prevention of cardiovascular disease. The optimal antiplatelet therapy for secondary prevention has been uncertain in this setting.
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Use of CNMs and Hospitalists
SYNOPSIS: A study assessing the effects of instituting a model of certified nurse midwife with MD laborist backup on a private patient population showed a decrease in cesarean section rate and an increase in vaginal birth after cesarean delivery rate without any change in combined neonatal outcome.
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Prognostic Value of Coronary Calcium on Standard Chest CT Scans
SYNOPSIS: Coronary calcium scan on standard CT scans performed for other indications is of equivalent prognostic value to that seen on ECG-gated coronary studies and should be included in radiology test reports.
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The Current Outlook for Cardiac Tamponade
SYNOPSIS: In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.
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The Best Rate Control Agent for Sepsis and Atrial Fibrillation
Sepsis and atrial fibrillation are common in the ICU, and the presence of both together is not a rare occurrence. Here's how to handle them.
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Leigh Syndrome: Insights and Implications from Advances in Next-generation Sequencing
Leigh syndrome is a genetically heterogeneous neurodevelopmental disorder. The application of next-generation sequencing has enabled a deeper understanding of the diverse nature of the genetic and molecular etiologies that give rise to the shared clinical phenotype of Leigh syndrome.
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Differentiating Sarcoidosis from Neuromyelitis Optic in Patients with Transverse Myelitis
Based on a retrospective analysis of 71 patients with an neuromyelitis optica spectrum disorder (n = 37) or sarcoidosis (n = 34), whose initial presentation was longitudinally extensive transverse myelitis (≥ 3 vertebral segments), the authors report clinical, radiologic, and laboratory findings that help distinguish one from the other.