Neurology
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Migraine with Aura and Systemic Right-to-Left Shunt: Risk for Stroke?
Right-to-left shunts, as detected by transcranial Doppler, are more common in patients with migraine with aura, but are not correlated with increased risk of silent posterior circulation infarcts or white matter lesions on MRI.
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Clinical Briefs
In this section: watching carefully for suicide risk; tackling chronic cough; and a new treatment for Peyronie's disease.
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Reslizumab Injection (Cinqair)
Reslizumab is indicated for add-on maintenance treatment of adult patients with severe asthma with eosinophilic phenotype.
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Longer Course Therapy for Lyme Disease Is Not Beneficial
A randomized, placebo-controlled clinical trial from the Netherlands found that longer-term antibiotic therapy for Lyme disease did not improve health-related quality of life compared to a standard course of treatment.
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Predicting Seizure Recurrence with Routine EEG After First Unprovoked Seizure
Using positive likelihood ratios, an adult and child with epileptiform discharges on electroencephalography were estimated to have a 77% and 66% probability, respectively, of recurrent seizures.
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Too Much of a Good Thing
In the United States in 2010 and 2011, an estimated 30% of outpatient oral antibiotic prescriptions may have been inappropriate, a finding that supports the need for establishing a goal for outpatient antibiotic stewardship.
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ECG Review: SVT in a 13-Year-Old Patient
The ECG in the figure below was obtained from an otherwise healthy 13-year-old boy. He was alert and hemodynamically stable at the time this ECG was recorded. How should one interpret this tracing?
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Clinical Briefs
In this section: comparing blood pressure monitoring techniques; DPP4 agents and heart failure; identifying at-risk groups for hypoglycemia.
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Infliximab-dyyb for Injection (Inflectra)
Infliximab-dyyb offers another, possibly less expensive, option for treatment of a number of autoimmune conditions.
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Early Chest CT Can Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.