Neurology
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Troponin Highly Prognostic in Decompensated Heart Failure With Preserved Ejection Fraction
Among patients with acute decompensated heart failure and preserved ejection fraction, elevated troponin is associated with worse in-hospital outcomes and long-term survival, independent of other predictors.
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Ventricular Tachycardia, Supraventricular Tachycardia With Right Bundle Branch Block, or Something Else?
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Clinical Briefs
In this section: recognizing signs of binge eating disorder; a closer look an antisocial behavioral problems; and treating sickle cell pain.
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Desmopressin Acetate Nasal Spray (Noctiva)
Desmopressin nasal spray is indicated for the treatment of nocturia due to nocturnal polyuria in adults who awaken at least twice per night to void.
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Polyneuropathy in the Metabolic Syndrome
The metabolic syndrome, independent of the diagnosis of diabetes, is associated with the development of polyneuropathy.
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Pioglitazone Improves Fibrosis Scores in Nonalcoholic Steatohepatitis Patients With and Without Diabetes
In a meta-analysis of eight studies (five pioglitazone, three rosiglitazone) involving 516 patients with biopsy-proven nonalcoholic steatohepatitis, pioglitazone was found to improve fibrosis between six and 24 months.
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Can Magnesium Cure Nocturnal Leg Cramps?
A small randomized, double-blind, placebo-controlled trial demonstrated that oral magnesium oxide was not superior to placebo for older adults suffering from nocturnal leg cramps.
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High-sensitivity Cardiac Troponin
In patients with new-onset chest pain without ECG evidence of an ST-elevation myocardial infarction, conversion to the use of a high-sensitivity troponin T assay with three-hour retesting in three hospitals was compared to maintaining the fourth-generation troponin T assay with six-hour retesting in three other hospitals. The use of high-sensitivity troponin T resulted in lower ED length of stay and costs, without increasing the use of coronary angiography or stress testing. -
Hyperoxia in ICU Patients May Cause Harm
Patients randomized to maintain oxygen saturation between 94-98% experienced better outcomes than patients allowed to receive partial pressure of oxygen > 150 mmHg. -
Hemoconcentration Associated with Lower Mortality in Acute Heart Failure
Among patients hospitalized for acute heart failure, hemoconcentration was associated with reduced 90-day mortality and may be a useful marker for guiding therapy.