Neurology
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Biochemical Pathogenesis of Intractable Epilepsy Due to Mesial Temporal Sclerosis
The concept that epilepsy arises from an imbalance between excitatory and inhibitory influences in epileptogenic tissue has become fundamental to further investigations of the pathophysiology of this disorder. The primary observation motivating the study of Eid and colleagues is that glutamate levels are elevated in patients with mesial temporal sclerosis (MTS), perhaps the most common cause of medication-resistant epilepsy. -
Pharmacology Watch: Sinus and Allergy Health Partnership Releases New Guidelines for Treatment of Bacterial Rhinosinusitis
New guidelines for the treatment of bacterial rhinosinusitis were published in the January supplement of Otolaryngology-Head and Neck Surgery by the Sinus and Allergy Health Partnership. -
Full March 2004 Issue in PDF
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Are Those White Matter Lesions in Migraine Real?
The possible association of migraine and stroke remains an active area of controversy in clinical neurology. Since migraines predominantly affect young people and the medications used can cause vasoconstriction, assessing the full vascular risk profile of migraine is important from a diagnostic and therapeutic point of view. To date, the literature is incomplete. -
Vitamin D Reduces Risk of MS
Munger and colleagues reviewed a database of 187,563 women enrolled in the Nurses Health Study, which longitudinally surveyed participants aged 25-55. There were 173 women with probable or definite multiple sclerosis (MS). Vitamin D intake was determined through the study questionnaire and 4 1-week diet records.