Neurology
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Thalidomide Neuropathy
Six patients are the focus of this report defining the neuropathic side effects of thalidomide treatment in multiple myeloma. All patients developed a pure or predominant sensory polyneuropathy while on thalidomide. Thalidomide can induce an axonal sensory neuropathy or, infrequently, a ganglionopathy. -
rt-PA Stroke Trials: Pooled Analysis and Opinion
Thrombolysis with intravenous rt-PA (IVrt-PA) is an effective treatment for strokes due to acute cerebral ischemia. This analysis of pooled data confirms that the sooner rt-PA is given to stroke patients, the greater the benefit, especially if started within 90 minutes. The results suggest a potential benefit beyond 3 hours but with a potential for an increased risk of death. -
Correction
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Pulmonary Embolism: Recent Advances in Diagnosis and Treatment Modalities, Part II
This second and final part of a series covers the topics of differential diagnosis that must be considered when a patient presents with symptoms consistent with PE, treatment, and considerations for prevention of this disease state. -
Full May 31, 2004, Issue in PDF
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Full April 5, 2004, Issue in PDF
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Pharmacology Watch: Estrogen Found to Not Affect Heart Disease, Breast Cancer
The NIH has halted the estrogen-alone wing of the Womens Health Initiative a year before its scheduled end. -
Full April 2004 Issue in PDF
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Clinical Briefs in Primary Care Supplement
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Another Tool for a Common Problem
Intranasal fluticasone helps sleep-disordered breathing in patients with allergic rhinitis.