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This multicenter prospective observational study reveals that transfusion practice in the critically ill has not changed in the past decade. 44% of ICU patients receive transfusions, and transfusions continue to be associated with worse clinical outcomes.
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Post hoc analysis of 3 large multicenter trials of patients with acute coronary syndromes demonstrates a strong association between transfusion and mortality.
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The FDA has approved a new drug for the management of alcohol dependence.
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Studies on HCV infection resolution show that PBMC HCV-RNA may remain, despite clearance of the virus from plasma.
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Headaches commonly attributed to sinus are very likely to be migraines.
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A new and as yet unpublished study has raised increased concern about the relationship between rofecoxib (Vioxx), Mercks blockbuster COX-2 inhibitor, and cardiovascular events.
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The ECG in the Figure was obtained from a 23-year-old male who presented with a several day history of atypical chest pain. His ECG was interpreted as consistent with an early repolarization variant. Should anything else be considered in the differential?
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The diagnosis of hyperhidrosis, or excessive sweating, is achieved by clinical inquiry rather than laboratory testing, though quantitative metrics are available for clinical research.
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Neck pain is common among the general population. Half of those patients who report this symptom have persistent complaints at 1 year. At particular risk for persistent neck pain are those ages 45-59 years, those with chronic low back pain, and patients who ride their bicycles regularly.
