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The FDA has approved a combination of 2 antiretrovirals, abacavir and lamivudine for the treatment of HIV-1 infections.
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Toenail Chromium in Men With Diabetes and Cardiovascular Disease; Combination of Fenofibrate and Rosiglitazone and HDL Cholesterol; Outcomes for Patients with Diet-Controlled Diabetes
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Use of ß-blockers is associated with reduced risk of
fracture. The magnitude of reduction is similar to that seen with use of thiazides.
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Treatment of systolic hypertension in older patients with systolic blood pressure of at least 160 mm Hg is supported by strong evidence. The evidence to support treatment of patients to the level of 140 mm Hg or those with baseline SBP of 140 to 159 mm Hg is less strong; thus, these treatment decisions should be more sensitive to patient preferences and tolerance of therapy.
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Methylprednisolone significantly improves the recovery of peripheral vestibular function in patients with vestibular neuritis, whereas valacyclovir does not.
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Among patients with severe carotid-artery stenosis and coexisting conditions, carotid stenting with the use of an emboli-protection device is not inferior to carotid endarterectomy.
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Although further technical improvements and prospective
clinical validation are required, these results suggest that mesial temporal memory activation, detected by fMRI during complex visual scene encoding, correlates with post-surgical memory outcome, and supports the notion that this approach will ultimately contribute to patient management.
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Syncytins proinflammatory properties in the nervous system demonstrate a novel role for an endogenous retrovirus protein, which may be a target for therapeutic intervention.
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Dopamine neurons derived from in vitro differentiated DJ-1 deficient embryonic stem cells showed decreased survival and increased sensitivity to oxidative stress.