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The greatest challenge for any potentially mortal disorder is to prove that therapeutic interventions reduce not only disease-specific mortality, but also all-cause mortality.
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Metabolomic profiling is a technique that measures and analyzes a large array of low molecular weight species in any chosen sample. Metabolomic analysis of plasma accurately distinguishes between subjects with Parkinson disease and healthy controls, thus providing a potential disease biomarker.
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Phrenic nerve conduction studies are technically difficult, but are useful in the evaluation of patients with diaphragmatic paralysis.
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Stop smoking drug Chantix rates stronger warning from FDA; Type 2 diabetes surgery on the way?; Vytorin study inconclusive; Influenza A virus found resistant to Tamiflu; FDA actions.
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Heavy alcohol consumption increases the risk of both ischemic and hemorrhagic stroke.
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Disruptive behaviors are a poor prognostic sign in patients with Alzheimer's disease.
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Anticoagulation for the prevention of venous thromboembolization is underutilized worldwide. Risk of short-term interruption of warfarin therapy appears small. Treatment with idraparinux increases hemorrhage risk, as compared with vitamin K antagonists.
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Genetic susceptibility to epilepsy is a complex, polygenetic matrix that is heavily influenced by environmental factors.