Neurology
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Elderly May Not Benefit From Statins for Primary Prevention
In an examination of the data from the much-publicized Systolic Blood Pressure Intervention Trial (SPRINT), the author found no benefit of statin therapy for primary prevention of cardiovascular events or all-cause mortality.
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A Possible New Treatment for HTLV-1-associated Myelopathy
Mogamulizumab reduces central nervous system inflammation and improves spasticity in patients with HTLV-1-associated myelopathy.
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Parsonage-Turner Syndrome: Where’s the Lesion?
SYNOPSIS: This careful analysis of MRI imaging of the brachial plexus in patients with well-defined Parsonage-Turner Syndrome showed that the lesions are in peripheral branches of the brachial plexus and not in the roots or cords.
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Lessons Learned From a Failed Anti-amyloid Trial for Alzheimer’s Disease
Despite the disappointing results in EXPEDITION 3, modifications of clinical trials for Alzheimer’s disease (AD) should be undertaken and trials targeting preclinical or early AD should continue with anti-amyloid agents.
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Postpartum Headache May Be a Symptom of a Serious Problem
Consultation for acute postpartum headache resulted in the diagnosis of a secondary cause of headache in almost three out of four women, with almost half of the secondary headaches due to a hypertensive disorder of pregnancy or to cerebrovascular disease.
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Coprescription of Triptans and SSRI-type Medications and the Serotonin Syndrome
A recent study provided reassurance that the use of triptan antimigraine medications with selective serotonin reuptake inhibitor and selective norepinephrine reuptake inhibitor antidepressants is safe.
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Autoimmune Encephalitis: Not Rare and Increasing
Detection of autoimmune encephalitis is increasing over time. According to the results from this population-based study, its prevalence and incidence are comparable to infectious encephalitis.
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Clinical Briefs
In this section: improving cardiovascular outcomes in type 2 diabetes patients; digging deeper into penicillin allergies; and treating osteoporosis.
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Apalutamide Tablets (Erleada)
Apalutamide is indicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer.
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Providers Facilitate Transmission of Resistant Organisms
A closer look at the role providers play in the transmission of carbapenem-resistant Enterobacteriaceae.