Neurology
RSSArticles
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Somatic Mutations in Cerebral Cortical Malformations
Targeted high-coverage sequencing for causal somatic mutations in patients with cortical malformations is more sensitive than traditional Sanger and whole-exome sequencing. -
Varicella-Zoster Virus and Fingolimod: Much Ado about Not Much?
The risk of varicella-zoster virus infections in patients treated with fingolimod is slightly higher than placebo, but is overall quite low. -
Cerebrospinal Fluid ß-Amyloid 42 vs Amyloid PET Imaging in the Diagnosis of Alzheimer’s Disease
Aß 42, measured in cerebrospinal fluid, may help determine whether patients have normal or increased cortical Aß deposition. Additionally, abnormal PET 18F-flutemetamol retention levels correlate with disease stage in patients with mild cognitive symptoms.
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Emergency Medicine Reports - Full January 4, 2015 Issue in PDF
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Hydrocodone Bitartrate Extended-release Tablets (Hysingla ER) CII
Hydrocodone is formulated to resist crushing, breaking, and dissolution and still retain some extended-release properties. -
Clinical Briefs
Because of its strong efficacy, long-term durability, and predictability when titrated with algorithms employed in clinical trials, basal insulin remains a mainstay of treatment for type 2 diabetes patients who are not able to attain or maintain glycemic control with oral agents alone. Because diabetes is a progressive disorder, even patients who are initially well-controlled on basal insulin will likely require “fine tuning” of their diabetes regimen, usually with agents that preferentially affect postprandial glucose levels. -
Another Reason Why Sitting is Just No Darn Good For You
Although not a life-threatening condition, benign prostatic hypertrophy (BPH) is one of the most annoying and troublesome problems that plagues aging males. -
Peri-procedural Management of New Oral Anticoagulants
Due to the short half-life and rapid onset of action of the new oral anticoagulants (NOACs), peri-procedural anticoagulant free time intervals should be shorter than with warfarin. Thus, there is uncertainty about the use of heparin bridging. -
Aortic Prosthetic Valve Type and Survival
Bioprosthetic aorta valves are recommended for those > 70 years of age because of their reduced durability compared to mechanical valves and mechanical prostheses, which are recommended for those < 60 years because bioprosthetic valves deteriorate more rapidly in younger individuals. -
Internal Medicine Alert - Full December 29, 2014 Issue in PDF