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The recent publication of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) and the continuing introduction of new psychoactive drugs create challenges for updated diagnostic and therapeutic choices for primary care patients.
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What is the Best Treatment for Cerebral Cavernous Malformations?
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In this prospective study, the authors use brain imaging criteria to determine whether acute febrile status results in acute hippocampal injury and potentially chronic hippocampal sclerosis.
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A new case-control study finds that increased levels of dichlorodiphenyldichloroethylene (DDE), which is the metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), are associated with an increased risk for Alzheimer's disease.
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Trochlear headaches should be considered in patients with new onset, constant, unilateral eye pain, especially when the pain is aggravated by eye movement.
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Most patients who develop cryoglobulinemia associated with hepatitis C infection will develop symptoms and signs of a symmetric, distal sensory neuropathy.
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Since the introduction of the vaccine against H. influenzae, there has been a significant decrease in the number of children presenting with epiglottitis. Although there is little evidence that the disease has increased in adults, clearly the percentage of cases in adults compared to children has increased. Further, there is greater recognition of milder cases with direct visualization and imaging.
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In a prospective study of 35 patients with newly diagnosed idiopathic intracranial hypertension confirmed by diagnostic lumbar puncture and treated with standard medication regimens, 43% of patients had excellent headache outcome at 12 months, with the major improvement seen within the first month of diagnosis.
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Unlike other neuromuscular disorders, physical exercise does not appear to worsen weakness in patients with Charcot-Marie-Tooth disease.
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At least 30% of strokes in China are caused by intracerebral hemorrhage, compared with approximately 10-15% in North America.
