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The FDA has approved the first free fatty acid form of omega-3. Previous formulations have been ethyl esters of omega-3-acids. The omega-3-carboxylic acid is a fish oil-derived mixture of 50-60% eicosapentaenoic acid (EPA) and 15-25% docosahexaenoic acid (DHA) along with other potentially active omega-3 fatty acids. It is marketed by AstraZeneca as Epanova.
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Severe obstructive sleep apnea is associated with a 30% increase in risk of incident diabetes, controlling for multiple relevant confounders.
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In a study of vulnerable elderly population at risk for disability, a structured, moderate-intensity physical activity program compared with a health education program significantly reduced major mobility disability.
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Administration of aspirin before surgery and throughout the early postsurgical period had no significant effect on the rate of composite of death or nonfatal myocardial infarction but did increase the risk of major bleeding.
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HIV may be acquired either vertically or horizontally. Vertical, or perinatal, transmission occurs when the virus is transmitted from mother to child in utero, during labor and delivery, or through breastfeeding. Horizontal transmission occurs when the virus is acquired behaviorally through the exchange of bodily fluids, typically through sexual contact or needle sharing.
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In a study of primary care patients, primary nonadherence was found to be common and may be improved by eliminating cost barriers as well as more frequent physician visits.
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The authors concluded that more than one of five simple risk factors for death would be an indication to explore advanced therapies in systolic HF patients < 80 years of age.
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