In total, 6,771 patients underwent screening for Staphylococcus aureus nasal colonization using real-time polymerase chain reaction (PCR). Of those, 1,251 patients were positive, 917 were enrolled in the trial, and 808 subsequently underwent a surgical procedure. The enrolled patients were treated with nasal mupirocin ointment plus body chlorhexidine baths (or placebo). Rates of S. aureus infection were 3.4% in the mupirocin-chlorhexidine group vs. 7.7% in the placebo group.
When ICU practitioners worked under senior clinicians who modeled good hand-hygiene practices, their own behavior with respect to hand hygiene improved.
Fixed dose of IVIg may not be effective in all patients with GBS.
Recurrent peptic ulcer bleeding was increased in patients with known cardiovascular or cerebrovascular disease when daily low-dose aspirin was continued along with proton-pump inhibitors, but overall mortality was significantly less during the 8-week follow-up.
