Neurology
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Recanalization Treatment in Pediatric Arterial Ischemic Stroke
In a population-based study from Switzerland, the authors found that recanalization treatment (intravenous thrombolysis or endovascular treatment) overall was safe without significant side effects or increased mortality compared to standard care.
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Hypercapnic Acidosis and Clinical Outcomes in Patients With Acute Brain Injury
In this multicenter retrospective study, hypercapnic acidosis was associated with worse clinical outcomes in mechanically ventilated patients with acute brain injury.
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Unilateral Scapular Winging
Scapular winging is an occasional finding on a neurological examination, rarely a chief complaint, and usually is caused by long thoracic nerve or spinal accessory nerve lesions.
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Initial Management of Patients With Medication-overuse Headache
As part of a randomized treatment trial for medication-overuse headache, a simple protocol that provided early advice on stopping excessive medications was effective in one-third of patients, even before any prophylactic medications were started.
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Which Is Better for Nonconvulsive Seizures: Lacosamide or Fosphenytoin?
Intravenous lacosamide was found to be noninferior to fosphenytoin in the treatment of nonconvulsive seizures in a prospective, multicenter, randomized clinical trial.
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Cannabidiol Oral Solution (Epidiolex)
Epidiolex is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients ≥ 2 years of age.
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A Negative Nares Screen for MRSA Helps Exclude MRSA Pneumonia
The authors of a meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia.
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Vitamin D and Glycemic Control in Patients With Type 2 Diabetes
Findings from a meta-analysis show vitamin D supplementation was associated with improved glycemic control in vitamin D-deficient or non-obese patients with type 2 diabetes.
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Tailored Anticoagulation for Paroxysmal Atrial Fibrillation
Intermittent anticoagulation guided by continuous assessment of arrhythmia status in patients with low-to-moderate risk did not result in any strokes or thromboembolic events over a relatively short follow-up period.
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Timing of Protein Intake Does Not Influence Muscle Mass or Strength
The timing of protein intake during or between meals does not play a role in anabolic response, muscle strength, or functional outcomes.