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Fabry disease, while rare across the general population, is not rare as a cause of small fiber neuropathy.
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Although subthalamic nucleus stimulation can improve motor functions in Parkinson's disease, this study showed that it degrades somatosensory temporal discrimination possibly by modifying central somatosensory processing.
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Peripheral nerve involvement is common in systemic amyloidosis and may be the initial clinical manifestation.
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FDA Advisory Committee recommends approval of dabigatran, safety of proton pump inhibitors, effectiveness of glucosamine and chondroitin, FDA Actions.
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Ever since 1796, when Edward Jenner introduced the world's first vaccine against smallpox, the role of vaccination has arguably become one of the most important advances in medicine.
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The incretin class of medications (exenatide, liraglutide, sitagliptin, saxagliptin) all share the favorable quality of not being associated with weight gain.
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A recombinant, polyethylene glycol (PEG) mammalian urate oxidase (uricase) has been approved by the FDA for treatment of hyperuricemia. Uricase metabolizes urate to allantoin, a water-soluble metabolite, which is cleared renally. Pegliticase is marketed by Savient Pharmaceuticals as Krystexxa™.