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Neurology

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Articles

  • Should Both Aspirin and Clopidogrel Be Used for the Treatment of Acute Coronary Syndromes?

    Jneid and associates critically analyzed the results of the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study and several other antiplatelet trials to provide guidance to the physician regarding the use of aspirin and/or clopidogrel in patients with ACS.
  • Prostate-Specific Antigen: To Test and Test and Test Again? Or Should We Test at All?

    Serum prostate-specific antigen (PSA) testing is frequently used in early detection programs for prostate cancer. While PSA testing has resulted in an increase in prostate cancer detection, its routine use has been questioned because of a lack of specificity. The objective of this study was to determine whether year-to-year fluctuations in prostate-specific antigen levels are due to natural variation and render a single PSA test result unreliable.
  • ECG Review: A 3-Beat Run in Lead V1

    The ECG in the Figure was obtained from a 57-year-old woman with palpitations. Is there a short run of VT (ventricular tachycardia) in lead V1? What else may be wrong with the tracing?
  • Clinical Briefs

    Metformin and Thiazolidinedione Use in Medicare Patients with Heart Failure; Alcohol Consumption Patterns and Biologic Markers of Glycemic Control Among 459 Women; Azelaic Acid Gel as a New Treatment for Papulopustular Rosacea
  • Pharmacology Update: Omalizumab Injection (Xolair)

    The FDA has approved Genentechs omalizumab, the first biotechnology drug for the treatment of asthma.
  • The Outpatient Bleeding Risk Index

    In 1998, Beyth and colleagues developed a modified outpatient bleeding risk index. In this prospective study conducted at the University of Ottawa, 222 patients with diagnosed pulmonary embolism or deep venous thrombosis were observed for an average of 18.5 months.
  • More Bad News for Folic Acid

    Elevated homocysteine levels have been associated with atherosclerosis. Folic acid supplementation is a simple, inexpensive way to reduce homocysteine levels, which has become popular for secondary prevention in patients with coronary artery disease (CAD), despite a paucity of long-term clinical trial data. Thus, Liem and colleagues studied 593 patients with stable CAD on statins who were randomized to open-label folic acid 0.5 mg/d or standard care, which included aggressive pursuit of lipid goals.
  • Pharmacology Watch: Nasally Administered Flu Vaccine Comes to United States

    Nasally Administered Flu Vaccine Comes to United States; Paxil: Not Recommended for Children; Prilosec Granted OTC Status; Finasteride and Prostate Cancer; Xolair: First Biologic Agent for Asthma; West Nile Virus Update; Study Shows COX-2 Inhibitors Appear Safe with Aspirin in Asthma Patients; Lamictal Approved for Bipolar Disorder
  • Full August 2003 Issue in PDF

  • Clinical Briefs in Primary Care Supplement

    Increase in Blood Glucose Concentration During Antihypertensive Treatment as a Predictor of Myocardial Infarction; Adverse Drug Events in Ambulatory Care; Prevention of Hip Fracture by External Hip Protectors; Rapid MRI vs Radiographs for Patients with Low Back Pain; Effectiveness of Anticholinergic Drugs Compared with Placebo in the Treatment of Overactive Bladder; A Randomized Trial of a Low Carbohydrate Diet for Obesity