Neurology
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Sufentanil Sublingual Tablets (Dsuvia) CII
Sufentanil sublingual tablets are for adults with acute pain that is severe enough to require an opioid analgesic for which different treatments have proven insufficient.
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Should Aspirin Be Used for Primary Prevention of Cardiovascular Events?
The conclusion from a series of groundbreaking studies is that primary prevention of cardiovascular disease and death by using daily low-dose aspirin is not recommended and should be reserved for those instances in which secondary prevention has been demonstrated to be effective in randomized, clinical trials.
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Costs and Consequences of Chronic Pain Among U.S. Adults
Annually, chronic pain accounts for an estimated $560 billion in direct medical costs, lost productivity, and disability programs. Identifying populations at risk is the first step for developing targeted interventions for pain management.
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Risk of Infective Endocarditis Revisited
In a comparison of patients with infective endocarditis (IE) and either bicuspid aortic valve (BAV) or mitral valve prolapse (MVP) vs. other IE patients at high or low-to-moderate risk of IE, BAV and MVP patients were more likely to exhibit viridans group streptococci infections of suspected odontogenic origin and cardiac complications at similar rates to high-risk patients.
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Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease
MRI of the brain in community-dwelling people (average age, 60 years) revealed that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.
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Oral Anticoagulant-associated ICH
Intracerebral hemorrhage is the most dangerous and feared complication of oral anticoagulation and leads to a high mortality. Debate continues about the relative risk of hemorrhage with two classes of oral anticoagulants.
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A Biomarker to Help With Neurologic Prognosis After Cardiac Arrest
Determining the prognosis of neurological outcome after cardiac arrest is notoriously difficult. Neurofilament light chain is a new potential biomarker, for which elevated levels in the spinal fluid or blood indicate axonal injury in several neurological diseases.
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Are Women More Prone to Brain Injury Than Men When Playing Soccer?
Repeated subconcussive injuries to the brain, such as “heading” the ball in soccer, result in more severe injury and slower recovery in women compared to men.
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Idiopathic Adult-onset Laryngeal Dystonia
Researchers demonstrated that isolated laryngeal dystonia in an Italian population can spread to contiguous regions, thus expanding knowledge of dystonia spread and phenomenology of this rare form of dystonia.
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Zika-associated vs. Non-Zika Guillain-Barré Syndrome
Guillain-Barré syndrome associated with Zika virus is similar to non-Zika virus cases in terms of severity of illness and prognosis around long-term recovery and disability.