Neurology Topics
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Is It Safe and Effective to Use Low-Dose Opioids Long Term to Treat Refractory RLS?
A review of two-year longitudinal data regarding efficacy and dose stability in refractory restless legs syndrome (RLS) patients treated with low-dose opioids shows that patients do not escalate their opiate dosage and that there is clinical and therapeutic stability in treating RLS with this therapeutic regimen.
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Stroke and a Wide QRS
The ECG in the figure is from an older man who presented with an acute stroke. He denied chest pain. Why is there QRS widening? What might be the clinical implications?
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Malpractice Lawsuits Allege ED Missed Intracranial Aneurysms
Failure to image patients is a relatively frequent cause of litigation, but it should be seen in context. It is not so much incorrect interpretations of imaging studies; rather, failure to consider the possibility of an aneurysm, resulting in an inadequate workup, is a more common allegation.
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Neurologists Try to Predict Cognitive Impairment Earlier
Researchers used easy memory tests among healthy participants to determine who might be more likely to need closer monitoring.
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Poor Sleep Patterns Could Raise Stroke Risk
Researchers provide another reason why patients should be resting well every night.
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Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease
Alterations in cerebrovascular insulin receptor isoform levels were associated with Alzheimer’s disease pathology and caused deficits in insulin signaling at the level of the blood-brain barrier.
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Influence of Vitamin Intake on Migraine Prevalence
Among participants experiencing severe headaches or migraine, those with severe headaches also reported a lower intake of thiamine and riboflavin, based on 24-hour recall of food intake.
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Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition
Researchers followed participants for three years and determined daily cocoa supplement use was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.
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Zavegepant Nasal Spray (Zavzpret)
Zavegepant can be prescribed to treat migraine, with or without aura, in adults.
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Bone Density as a Dementia Risk Indicator
Researchers found some associations between bone density loss and a higher risk of developing dementia.