Neurology/Neurosurgery General
RSSArticles
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REM Behavior Disorder — A Unique Window into the Mysteries of Neurodegenerative Disease
REM behavior disorder may precede α-synucleinopathies by decades and may be a biomarker of future disease.
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Hypothermia after Acute Traumatic Brain Injury Revisited
Hypothermia therapy is effective after severe traumatic brain injury for patients ages 50 years and younger. However, mortality was increased in patients treated with hypothermia who had diffuse injury with swelling on CT.
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Relationship Between Brain MRI Biomarkers and Cognition
In a prospective, longitudinal, cohort study of an asymptomatic, multi-ethnic Dallas community, brain MRI biomarkers measuring volume were associated with cognitive functions, as measured by the Montreal Cognitive Assessment.
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Neurologic Disease and Criminal Behavior – A Medicolegal Conundrum
Patients with frontotemporal dementia, primary progressive aphasia, and Huntington’s disease exhibited antisocial and/or criminal behavior.
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Autologous Hematopoietic Stem Cell Transplant for Relapsing-Remitting MS
Interim analysis at 3 years post-treatment of a study of high-dose immunosuppression and autologous hematopoietic stem cell transplant for relapsing remitting-multiple sclerosis demonstrates sustained disease control but also shows potential risks associated with this treatment.
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Surgical Treatment of Brain Metastases
Surgical removal of brain metastases remains an important part of palliative therapy for metastatic cancer. -
Women with Migraine: Options for Decreasing Disability
Menstrually related migraine is difficult to treat and options are limited. Hormonal manipulation is controversial and unproven. -
Teriflunomide: A New Oral Agent for the Treatment of Multiple Sclerosis
Teriflunomide, an orally administered inhibitor of dihydro-orotate dehydrogenase, was found to be superior to placebo in reducing relapses in a 2-year, Phase 3 clinical trial in patients with multiple sclerosis. -
Clinical Briefs in Primary Care Supplement
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Stroke Alert: A Review of Current Clinical Stroke Literature
Forty-nine clinical centers and 18 positron emission tomography (PET) centers in the United States and Canada participated in a randomized, blinded-adjudication clinical treatment trial of 195 patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) who also had hemodynamic cerebral ischemia identified by ipsilateral increased oxygen extraction fraction measured by PET.