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Detailed neuropathological investigation of patients with sensory neuronopathy and polymerase γ mutations revealed evidence of posterior column atrophy in spinal cord sections and marked neuronal cell loss with severe mitochondrial biochemical abnormalities (involving respiratory chain complexes I and IV) in the dorsal root ganglia.
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Small fiber neuropathy (SFN) is a relatively common disorder that affects small somatic and/or autonomic nerves. Known causes include diabetes, vitamin B12 deficiency, and Sjogren's syndrome among others, although the condition is idiopathic in most cases.
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This study validated that anti-aquaporin-4 antibodies are highly specific (99.8%) for Devic's disease and related disorders when tested in a large series of miscellaneous autoimmune and non-autoimmune systemic diseases.
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Needle EMG is safe in patients who are taking therapeutic doses of antiplatelet or anticoagulant medications.
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CLIPPERS is a recently described steroid- responsive neurological syndrome manifested by subacute progressive cerebellar and brainstem inflammation with characteristic MRI appearance.
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New treatment for TB; safety of dabigatran; quality of antidepressants; systolic hypertension treatment; and FDA actions.
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A small percentage of patients taking statins may develop muscle symptoms (pain and weakness) but elevated CK is rare.
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This clinical study evaluated patients with posterior reversible encephalopathy syndrome to determine the kind of seizures they experienced, abnormalities on EEG, and to correlate this with findings on neuroimaging (MRI).
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Neurological disease affecting the non-dominant frontal lobe has been associated with a syndrome of "delusional jealousy," referred to as Othello syndrome.