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This case series of patients with painful legs and moving toes is the largest to date and describes association with female gender, peripheral neuropathy and radiculopathy, cancer, and autoimmune disorders. Neurophysiology suggests an additional central component, supporting recruitment of a spinal cord or brainstem generator.
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Biomarkers in the cerebrospinal fluid open the possibility of diagnosing early or even presymptomatic cases of Alzheimer's disease, thereby expanding the potential window for therapy.
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Intravenous erythropoietin therapy appears to reduce retina nerve fiber layer thinning 16 weeks after onset of optic neuritis, but larger studies needed to detect differences in visual outcome.
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Thrombolysis for Ischemic Stroke Associated with Cervical Artery Dissection Does Not Improve Overall Outcome; In Patients with Lacunar Strokes, Addition of Clopidogrel to Aspirin Does Not Reduce Risk of Recurrent Stroke; Risk of Restenosis After Carotid Artery Stenting and Carotid Endarterectomy Are Similar
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Behçet's disease, while rare in North America, should be considered when appropriate, in light of the extensive travel and immigration patterns around the world.
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Mesenchymal stem cells for the treatment of multiple system atrophy is a promising potential therapy, but requires further investigation regarding both safety and efficacy.
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Analysis of intracranial pressure complexity using a non-linear method of multiscale entropy shows that it correlates with outcome after traumatic brain injury.
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In this long-term, population-based patient series, the authors explore the natural course of drug-resistant epilepsy and explore whether remission can be predicted by clinical features.
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Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.