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Intracranial stenting is a promising new technology for secondary stroke prevention, but needs to be studied in a randomized trial against best medical therapy.
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Elderly patients with glioblastoma, who are independent in activities of daily living, will have a longer survival with good quality of life if treated with radiotherapy rather than supportive care, alone.
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Several CSF biomarkers, sphingomyelin, sphingomyelinase, ceramide, 4-hydroxynonenal, and vitamin E, are associated with the development of HIV dementia in patients being treated with highly active antiretroviral therapy (HAART).
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MRI is more sensitive than CT for detecting acute ischemia and can detect acute hemorrhage with equal sensitivity to CT.
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Occipital nerve stimulation appears to decrease the cluster pain and attack frequency in most, but not all, patients with chronic drug-resistant cluster headaches.
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Many patients with Parkinson disease have normalization of movement during REM sleep, similar to the beneficial effects of levodopa while they are awake.
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IVIG is safe and effective for worsening MG, but has no effect on the natural course of Miller Fisher syndrome.
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These 2 clinical trials comparing Standard and New Antiepileptic Drugs (SANAD) showed that for partial epilepsy, lamotrigine was clinically better than carbamazepine, and that for generalized and unclassifiable epilepsy, valproate was better tolerated than topiramate and more efficacious than lamotrigine.