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Deep brain stimulation significantly increases "on" time, reduces dyskinesias, reduces "off" time, and improves various quality-of-life measures compared with best medical therapy in patients with moderate to advanced Parkinson's disease.
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FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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In this retrospective study, the authors describe the prevalence and significance of both electrographic seizures and periodic discharges in critically ill patients with central nervous system infections.
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Although the active immunization trial was stopped because of severe side effects, autopsy studies revealed that soluble plaque amyloid moves to the perivascular spaces as an initial step before it is cleared from the brain.
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Chronic treatment with warfarin, prior to presentation with an ischemic stroke, is associated with a significant decrease in infarct size.
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Great progress has been made in identifying the underlying genetic defects in congenital myopathies.
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Sleep disordered breathing occurs in most acute stroke patients and may contribute to morbidity
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Telcagepant, a new oral calcitonin gene-related peptide receptor antagonist, has similar efficacy and better tolerability for acute migraine headaches as compared to a triptan.
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Serial MRI measurements can be used to map the pattern of regional brain atrophy in a variety of neurologic disease states. Using robust techniques that minimize the subjectivity of morphometric analysis, Scahill and colleagues compared rates and regional distribution of brain atrophy in 4 presymptomatic patients, 10 with mild Alzheimers Disease (AD), 12 with moderate AD, and age-matched controls.