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Fingolimod, a novel immunomodulating agent that can be taken orally, reduces the number of clinical relapses and MRI lesions in patients with multiple sclerosis.
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Severe tongue protrusion dystonia is disabling and occasionally life-threatening, and may suggest either a secondary cause or particular heredodegenerative diseases.
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Sporadic Creutzfeldt-Jakob disease (CJD) has multiple subtypes, and the subtype has an effect on the sensitivity of commonly utilized diagnostic tests in the workup of CJD.
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Deep brain stimulation of the subthalamic nucleus improved "off" motor symptoms and quality of life in advanced Parkinson's disease, but was associated with an increased rate of serious adverse events.
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Wait and see prescriptions (WASP) is a new concept for the treatment of otitis media in children.
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α-synuclein mutations leading to Parkinson's disease are extremely rare. However, based upon this study, variability in the gene promoter may account for up to 3% of the risk of Parkinson's disease in the general population.
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A team from UCSF recently reviewed company documents that were entered into the public record as a result of litigation over the promotion of gabapentin (Neurontin) between 1994 and 1998.
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The neurological risk of cardiac surgery is still not well characterized, but post-operative strokes occur in 3-9% of patients. A decrease in intra-operative blood pressure and increased cardiopulmonary bypass time may result in watershed infarcts.